Data-Dependent Acquisition and Database-Driven Efficient Peak Annotation for the Comprehensive Profiling and Characterization of the Multicomponents from Compound Xueshuantong Capsule by UHPLC/IM-QTOF-MS

The state of the art ion mobility quadrupole time of flight (IM-QTOF) mass spectrometer coupled with ultra-high performance liquid chromatography (UHPLC) can offer four-dimensional information supporting the comprehensive multicomponent characterization of Inlet Hose Nut traditional Chinese medicine (TCM).Compound Xueshuantong Capsule (CXC) is a fo

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Effects of Two Types of Simple and Sensor Thoracolumbosacral Braces on Ground Reaction Force Components during Walking in Males with Kyphosis

Background and Objective: One of the ways to correct kyphosis is to use braces.This study was done to determine the effects of two types of simple and sensor thoracolumbosacral braces on ground reaction force components during walking in males with kyphosis.Methods: In this quasi-experimental study, 15 males with kyphosis did three Inlet Hose Nut w

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PharmOmics: A species- and tissue-specific drug signature database and gene-network-based drug repositioning tool

Summary: Drug development has been hampered by a high failure rate in clinical trials due to our incomplete understanding of drug functions across organs and species.Therefore, elucidating species- and tissue-specific drug functions can provide insights into therapeutic efficacy, potential adverse effects, and interspecies differences necessary for

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